REST Antikörper (N-Term)

Produktnummer ABIN5518090

Produktdetails anti-REST Antikörper

Target: REST (RE1-Silencing Transcription Factor (REST))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser REST Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SGSSTAEEGD FSKGPIRCDR CGYNTNRYDH YTAHLKHHTR AGDNERVYKC

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against REST. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human REST

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu REST

Target: REST (RE1-Silencing Transcription Factor (REST))

Andere Bezeichnung: REST (REST Produkte)

Synonyme: NRSF antikoerper, XBR antikoerper, 2610008J04Rik antikoerper, AA407358 antikoerper, xbr antikoerper, nrsf antikoerper, rest antikoerper, resta antikoerper, REST antikoerper, RE1 silencing transcription factor antikoerper, RE1-silencing transcription factor antikoerper, RE1-silencing transcription factor S homeolog antikoerper, REST antikoerper, Rest antikoerper, rest.S antikoerper, rest antikoerper, LOC615792 antikoerper

Hintergrund: This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described.

Alias Symbols: REST, NRSF, XBR,

Protein Interaction Partner: BTRC, UBC, FBXW11, CSNK1E, NEDD8, EHMT2, EIF4A3, FBXW4, FBXW7, FBXW5, FBXW8, FBXW2, SIN3A, TERF2, GRIA2, SUB1, GTF2B, Tbp, SIN3B, HDAC1, RCOR1, SP1, SMARCE1, SMARCC2, SMARCA4, CDYL, HDAC5, HDAC4, HTT, NCOR1, KDM5C, RNF2, HDAC2, STMN2, GRM2, CTDSP1,

Protein Size: 1097

Gen-ID: 5978

NCBI Accession: NP_005603

UniProt: Q13127

Pathways: Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity