Caspase 6 Antikörper (N-Term)

Produktnummer ABIN5518670

Produktdetails anti-Caspase 6 Antikörper

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Bindungsspezifität: AA 7-27, N-Term

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Verwendungszweck: Rabbit IgG polyclonal antibody for Caspase-6(CASP6) detection. Tested with WB, IHC-P, IHC-F in Mouse, Rat.

Sequenz: FYRSREVLDP AEQYKMDHKR R

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Caspase-6(CASP6) detection. Tested with WB, IHC-P, IHC-F in Mouse, Rat.
Gene Name: caspase 6, apoptosis-related cysteine peptidase
Protein Name: Caspase-6

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of rat Caspase-6(P18)(7-27aa FYRSREVLDPAEQYKMDHKRR), different from the related mouse sequence by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu Caspase 6

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Andere Bezeichnung: CASP6 (CASP6 Produkte)

Synonyme: xCaspase-6 antikoerper, mch2 antikoerper, caspase-6 antikoerper, zgc:112960 antikoerper, CASP6 antikoerper, casp6 antikoerper, Mch2 antikoerper, mCASP-6 antikoerper, MCH2 antikoerper, caspase 6 L homeolog antikoerper, caspase 6 antikoerper, caspase 6, apoptosis-related cysteine peptidase antikoerper, group XIIA secretory phospholipase A2 antikoerper, caspase-6 antikoerper, casp6.L antikoerper, casp6 antikoerper, CASP6 antikoerper, CpipJ_CPIJ017008 antikoerper, Casp6 antikoerper

Hintergrund: Caspase 6 is an enzyme that in humans is encoded by the caspase 6 gene. This gene encodes a protein that is a member of the cysteine-aspartic acid protease(caspase) family. Using radiation hybrid mapping, the Caspase 6 gene is localized to human chromosome 4q25-q26. Caspase 6 functions as a downstream enzyme in the caspase activation cascade. And Caspase 6 can cleave lamin A to its signature apoptotic fragment.

Synonyms: Apoptosis Related Cysteine Protease antibody|Apoptotic cysteine protease MCH2 antibody|Apoptotic protease MCH 2 antibody|Apoptotic protease Mch-2 antibody|Apoptotic protease MCH2 antibody|Casp 6 antibody|CASP-6 antibody|Casp6 antibody|Caspase 6 antibody|Caspase 6 apoptosis related cysteine protease antibody|Caspase 6 precursor antibody|Caspase 6, apoptosis related cysteine peptidase antibody|Caspase-6 subunit p18 antibody|Caspase6 antibody|Human cysteine protease Mch2 isoform alpha antibody|Mch 2 antibody|Mch2 antibody|OTTHUMP00000162742 antibody|OTTHUMP00000162743 antibody

UniProt: O35397

Pathways: Apoptose, Caspase Kaskade in der Apoptose