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APEX2 Antikörper (AA 102-210)

APEX2 Reaktivität: Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5518737
  • Target Alle APEX2 Antikörper anzeigen
    APEX2 (APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 102-210
    Reaktivität
    • 21
    • 1
    • 1
    Ratte
    Wirt
    • 20
    • 2
    Kaninchen
    Klonalität
    • 22
    Polyklonal
    Konjugat
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser APEX2 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 15
    • 15
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Rabbit IgG polyclonal antibody for DNA-(apurinic or apyrimidinic site) lyase 2(APEX2) detection. Tested with WB in Human,Rat.
    Kreuzreaktivität (Details)
    Predicted Cross Reactivity: human
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for DNA-(apurinic or apyrimidinic site) lyase 2(APEX2) detection. Tested with WB in Human,Rat.
    Gene Name: APEX nuclease (apurinic/apyrimidinic endonuclease) 2
    Protein Name: DNA-(apurinic or apyrimidinic site) lyase 2
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human APEX2 recombinant protein (Position: L102-A210). Human APEX2 shares 91.7% amino acid (aa) sequence identity with mouse APEX2.
    Isotyp
    IgG
    Top Product
    Discover our top product APEX2 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    APEX2 (APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2))
    Andere Bezeichnung
    APEX2 (APEX2 Produkte)
    Synonyme
    APE2 antikoerper, APEXL2 antikoerper, XTH2 antikoerper, ape2 antikoerper, apexl2 antikoerper, xth2 antikoerper, zgc:55889 antikoerper, C430040P13Rik antikoerper, apurinic/apyrimidinic endodeoxyribonuclease 2 antikoerper, APEX nuclease (apurinic/apyrimidinic endonuclease) 2 antikoerper, apurinic/apyrimidinic endodeoxyribonuclease 2 L homeolog antikoerper, apurinic/apyrimidinic endonuclease 2 antikoerper, APEX2 antikoerper, apex2 antikoerper, apex2.L antikoerper, Apex2 antikoerper
    Hintergrund
    APEX2, also called apurinic/apyrimidinic endonuclease like-2, is a member of the apurinic/apyrimidinic (AP) family of endonucleases that initiate the repair of AP sites formed by spontaneous hydrolysis of the N-glycosylic bond, mutagen-induced base release, or damaged-base excision by a DNA repair glycosylase. RT-PCR detected APEX2 expression in HeLa cells, Jurkat cells, and human kidney, brain and fetal brain tissue. The APEX2 gene is mapped to chromosome Xp11.21. APEX2 participates in both nuclear and mitochondrial base excision repair (BER) and it can play a role in processing 3-prime-damaged termini or 3-prime-mismatched nucleotides. Additionally, APEX2 displayed weaker AP site-specific and 3-prime nuclease activities compared to APEX1.

    Synonyms: AP endonuclease XTH2 | APE2 | APE2 | XTH2 | APEX nuclease-like 2 | APEX2 | APEXL 2 | APEXL2 | Q9UBZ4 | XTH 2
    Gen-ID
    27301
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