Muscarinic Acetylcholine Receptor M2 Antikörper (C-Term)
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- Target Alle Muscarinic Acetylcholine Receptor M2 (CHRM2) Antikörper anzeigen
- Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))
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Bindungsspezifität
- AA 352-376, C-Term
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Muscarinic Acetylcholine Receptor M2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Muscarinic acetylcholine receptor M2(CHRM2) detection. Tested with WB in Human,Mouse,Rat.
- Sequenz
- QNGDEKQNIV ARKIVKMTKQ PAKKK
- Kreuzreaktivität (Details)
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Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - Produktmerkmale
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Rabbit IgG polyclonal antibody for Muscarinic acetylcholine receptor M2(CHRM2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: cholinergic receptor, muscarinic 2
Protein Name: Muscarinic acetylcholine receptor M2 - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human CHRM2 (352-376aa QNGDEKQNIVARKIVKMTKQPAKKK), identical to the related mouse and rat sequences.
- Isotyp
- IgG
- Top Product
- Discover our top product CHRM2 Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))
- Andere Bezeichnung
- CHRM2 (CHRM2 Produkte)
- Synonyme
- HM2 antikoerper, AChR-M2 antikoerper, Chrm-2 antikoerper, M2 antikoerper, chrm2 antikoerper, Acm2 antikoerper, GPM2 antikoerper, cholinergic receptor muscarinic 2 antikoerper, cholinergic receptor, muscarinic 2, cardiac antikoerper, cholinergic receptor, muscarinic 2a antikoerper, cholinergic receptor, muscarinic 2 antikoerper, CHRM2 antikoerper, Chrm2 antikoerper, chrm2a antikoerper
- Hintergrund
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The muscarinic acetylcholine receptor M2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor that in humans is encoded by the CHRM2 gene. The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.
Synonyms: Acm2 | ACM2 | CHRM 2 | CHRM2 | M2 muscarinic receptor | Muscarinic Acetylcholine Receptor 2 | Muscarinic M2 receptor | P08172 - Gen-ID
- 1129
- UniProt
- P08172
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