GAS6 Antikörper (AA 488-660)

Produktnummer ABIN5518836

Produktdetails anti-GAS6 Antikörper

Target: GAS6 (Growth Arrest-Specific 6 (GAS6))

Bindungsspezifität: AA 488-660

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GAS6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Growth arrest-specific protein 6(GAS6) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Kreuzreaktivität (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Growth arrest-specific protein 6(GAS6) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: growth arrest specific 6
Protein Name: Growth arrest-specific protein 6

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human GAS 6 recombinant protein (Position: M488-S660). Human GAS 6 shares 79.7% and 81.4% amino acid (aa) sequence identity with mouse and rat GAS 6, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu GAS6

Target: GAS6 (Growth Arrest-Specific 6 (GAS6))

Andere Bezeichnung: GAS6 (GAS6 Produkte)

Synonyme: fj34a12 antikoerper, zgc:63860 antikoerper, wu:fj34a12 antikoerper, MGC68463 antikoerper, gas6 antikoerper, MGC83872 antikoerper, GAS6 antikoerper, Gas-6 antikoerper, AXLLG antikoerper, AXSF antikoerper, growth arrest specific 6 antikoerper, growth arrest-specific 6 antikoerper, growth arrest specific 6 L homeolog antikoerper, growth arrest specific 6 S homeolog antikoerper, GAS6 antikoerper, gas6 antikoerper, gas6.L antikoerper, gas6.S antikoerper, Gas6 antikoerper

Hintergrund: Growth arrest-specific 6, also known as GAS6, is a human gene coding for the Gas6 protein. It is similar to the Protein S with the same domain organization and 43 % amino acid identity. It was originally found as a gene upregulated by growth arrested fibroblasts. This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker. Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia.

Synonyms: AXLLG | AXS F | AXSF | FLJ34709 | Gas 6 | GAS-6 | Gas6 | Q14393

Gen-ID: 2621

UniProt: Q14393

Pathways: RTK Signalweg, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response