HSD17B4 Antikörper (AA 510-736)

Produktnummer ABIN5518845

Produktdetails anti-HSD17B4 Antikörper

Target: HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))

Bindungsspezifität: AA 510-736

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Peroxisomal multifunctional enzyme type 2(HSD17B4) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Peroxisomal multifunctional enzyme type 2(HSD17B4) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: hydroxysteroid (17-beta) dehydrogenase 4
Protein Name: Peroxisomal multifunctional enzyme type 2

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human HSD17B4 recombinant protein (Position: D510-L736). Human HSD17B4 shares 87.7% and 89% amino acid (aa) sequence identity with mouse and rat HSD17B4, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu HSD17B4

Target: HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))

Andere Bezeichnung: HSD17B4 (HSD17B4 Produkte)

Synonyme: zgc:55545 antikoerper, zgc:77300 antikoerper, CG3415 antikoerper, DmMFE-2 antikoerper, Dmel\\CG3415 antikoerper, MFE-2 antikoerper, DBP antikoerper, MPF-2 antikoerper, PRLTS1 antikoerper, SDR8C1 antikoerper, 17-beta-HSD antikoerper, 17[b]-HSD antikoerper, 4 antikoerper, MFP2 antikoerper, Mfp-2 antikoerper, perMFE-2 antikoerper, hydroxysteroid (17-beta) dehydrogenase 4 antikoerper, hydroxysteroid 17-beta dehydrogenase 4 antikoerper, peroxisomal Multifunctional enzyme type 2 antikoerper, hsd17b4 antikoerper, HSD17B4 antikoerper, Mfe2 antikoerper, Hsd17b4 antikoerper

Hintergrund: Peroxisomal multifunctional enzyme type 2 is a protein that in humans is encoded by the HSD17B4 gene. The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Synonyms: 17 beta HSD 4 | 17 beta HSD IV | 17-beta-HSD 4 | 3-alpha | 7-alpha | DBP | EDH17B4 | Hsd17b4 | MFE2 | MFE-2 | MFE 2 | PRLTS1 | SDR8C1 | P51659

Gen-ID: 3295

UniProt: P51659

Pathways: Monocarboxylic Acid Catabolic Process