XDH Antikörper (AA 2-343)

Produktnummer ABIN5518967

Produktdetails anti-XDH Antikörper

Target: XDH (Xanthine Dehydrogenase (XDH))

Bindungsspezifität: AA 2-343

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XDH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Xanthine dehydrogenase/oxidase(XDH) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Kreuzreaktivität (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Xanthine dehydrogenase/oxidase(XDH) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: xanthine dehydrogenase
Protein Name: Xanthine dehydrogenase/oxidase

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human Xanthine Oxidase recombinant protein (Position: T2-K343). Human Xanthine Oxidase shares 86.8% and 89.2% amino acid (aa) sequence identity with mouse and rat Xanthine Oxidase, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-XDH Antikörper (ABIN5518967)

Huang, Zhu, Li, Sui, Min: "Effect of Blueberry Anthocyanins Malvidin and Glycosides on the Antioxidant Properties in Endothelial Cells." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 1591803, (2017) (PubMed).

Details zu XDH

Target: XDH (Xanthine Dehydrogenase (XDH))

Andere Bezeichnung: XDH (XDH Produkte)

Synonyme: XO antikoerper, XOR antikoerper, Xor antikoerper, Xox-1 antikoerper, Xox1 antikoerper, XDH antikoerper, im:7146167 antikoerper, DDBDRAFT_0219626 antikoerper, DDBDRAFT_0230176 antikoerper, DDB_0219626 antikoerper, DDB_0230176 antikoerper, xanthine dehydrogenase antikoerper, xanthine dehydrogenase/oxidase antikoerper, Xanthine dehydrogenase antikoerper, XDH antikoerper, Xdh antikoerper, xdh antikoerper, LOC576712 antikoerper, Trebr_1754 antikoerper

Hintergrund: Xanthine dehydrogenase, also known as XDH, is a protein that, in humans, is encoded by the XDH gene. Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.

Synonyms: Xanthine dehydrogenase/oxidase, Xanthine dehydrogenase, XD

Gen-ID: 7498

UniProt: P47989

Pathways: Positive Regulation of Endopeptidase Activity