FLT3 Antikörper (AA 62-295)

Produktnummer ABIN5518988

Produktdetails anti-FLT3 Antikörper

Target: FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

Bindungsspezifität: AA 62-295

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FLT3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Flt3 / CD135 detection. Tested with WB, IHC-P, Direct ELISA in Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Flt3 / CD135 detection. Tested with WB, IHC-P, Direct ELISA in Mouse,Rat.
Gene Name: FMS-like tyrosine kinase 3
Protein Name: Receptor-type tyrosine-protein kinase FLT3

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived mouse Flt3 / CD135 recombinant protein (Position: E62-E295).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu FLT3

Target: FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

Andere Bezeichnung: Flt3 (FLT3 Produkte)

Synonyme: FLT3 antikoerper, B230315G04 antikoerper, CD135 antikoerper, Flk-2 antikoerper, Flk2 antikoerper, Flt-3 antikoerper, Ly72 antikoerper, wmfl antikoerper, FLK-2 antikoerper, FLK2 antikoerper, STK1 antikoerper, fms related tyrosine kinase 3 antikoerper, FMS-like tyrosine kinase 3 antikoerper, fms-related tyrosine kinase 3 antikoerper, FLT3 antikoerper, Flt3 antikoerper

Hintergrund: Cluster of differentiation antigen 135 (CD135) also known as fms like tyrosine kinase 3 (FLT-3), receptor-type tyrosine-protein kinase FLT3, or fetal liver kinase-2 (Flk2) is a protein that in humans is encoded by the FLT3 gene. This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow.

Synonyms: Receptor-type tyrosine-protein kinase FLT3, FL cytokine receptor, Fetal liver kinase 2, FLK-2, Fms-like tyrosine kinase 3, FLT-3, Tyrosine-protein kinase receptor flk-2, CD135, Flt3, Flk-2, Flt-3

Gen-ID: 14255

UniProt: Q00342

Pathways: RTK Signalweg