PARK7/DJ1 Antikörper (AA 2-189)
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- Target Alle PARK7/DJ1 (PARK7) Antikörper anzeigen
- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
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Bindungsspezifität
- AA 2-189
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PARK7/DJ1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- Rabbit IgG polyclonal antibody for PARK7 / DJ1 detection. Tested with WB, IHC-P, ELISA(Cap) in Mouse,Rat.
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for PARK7 / DJ1 detection. Tested with WB, IHC-P, ELISA(Cap) in Mouse,Rat.
Gene Name: Parkinson disease (autosomal recessive, early onset) 7
Protein Name: Protein DJ-1 - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- E. coli-derived mouse PARK7 / DJ1 recombinant protein (Position: A2-D189).
- Isotyp
- IgG
- Top Product
- Discover our top product PARK7 Primärantikörper
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- Applikationshinweise
- Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
- Kommentare
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Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
- Andere Bezeichnung
- Park7 (PARK7 Produkte)
- Synonyme
- DJ-1 antikoerper, DJ1 antikoerper, CAP1 antikoerper, Dj1 antikoerper, SP22 antikoerper, dj1 antikoerper, zgc:103725 antikoerper, park7b antikoerper, park7 antikoerper, park7a antikoerper, Parkinsonism associated deglycase antikoerper, Parkinson disease (autosomal recessive, early onset) 7 antikoerper, parkinson protein 7 antikoerper, parkinson protein 7 S homeolog antikoerper, parkinson protein 7 L homeolog antikoerper, PARK7 antikoerper, Park7 antikoerper, park7 antikoerper, park7.S antikoerper, park7.L antikoerper
- Hintergrund
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Parkinson disease (autosomal recessive, early onset) 7, also known as DJ1, is a protein which in humans is encoded by the PARK7 gene. PARK7 belongs to the peptidase C56 family of proteins. PARK7 is mapped to chromosome 1p36. It acts as a positive regulator of androgen receptor-dependent transcription. It is also involved in tumorigenesis and in maintaining mitochondrial homeostasis. This gene may also function as a redox-sensitive chaperone, as a sensor foroxidative stress, and it apparently protects neurons against oxidative stress and cell death. It has been found that PARK7 mutations that impair transcriptional coactivator function can render dopaminergic neurons vulnerable to apoptosis and may contribute to the pathogenesis of Parkinson disease.
Synonyms: Protein DJ-1, DJ-1, Parkinson disease protein 7 homolog, Protein deglycase DJ-1 - Gen-ID
- 57320
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
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