Tissue factor Antikörper

Produktnummer ABIN5526905

Produktdetails anti-Tissue factor Antikörper

Target: Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Tissue factor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: The mouse monoclonal antibody HTF-1, also known as HTF1-7B8, recognizes an extracellular epitope of CD142 (tissue factor, coagulation factor III), a type I glycoprotein expressed on endothelial cells, monocytes, macrophages, and platelets upon induction by inflammatory mediators, and expressed constitutively by some tumors, the vasculature, placenta, kidney, and central nervous system.

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Human brain tissue factor (CD142)

Klon: HTF-1

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 3-12 μg/mL.
Western blotting: Reducing conditions preferred.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu Tissue factor

Target: Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))

Andere Bezeichnung: CD142 (F3 Produkte)

Synonyme: CD142 antikoerper, TF antikoerper, TFA antikoerper, PRO1557 antikoerper, PRO2086 antikoerper, TFQTL1 antikoerper, f3 antikoerper, AA409063 antikoerper, Cf-3 antikoerper, Cf3 antikoerper, tf antikoerper, zgc:112151 antikoerper, coagulation factor III, tissue factor antikoerper, transferrin antikoerper, coagulation factor IIIa antikoerper, coagulation factor III antikoerper, tissue factor antikoerper, coagulation factor IIIb antikoerper, coagulation factor III (thromboplastin, tissue factor) S homeolog antikoerper, F3 antikoerper, TF antikoerper, f3a antikoerper, tf antikoerper, f3b antikoerper, f3.S antikoerper

Hintergrund: Coagulation factor III, tissue factor,CD142, also known as coagulation factor III, tissue thromboplastin, and tissue factor. It is a transmembrane glycoprotein, which enables cells to initiate the blood coagulation cascades, and functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. It is the only one factor in the coagulation pathway for which a congenital deficiency has not been described.,F3, tissue factor, tissue thromboplastin, coagulation factor III, TF, TFA

Gen-ID: 2152

UniProt: P13726

Pathways: Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling