PYGM Antikörper (C-Term)

Produktnummer ABIN5531905

Produktdetails anti-PYGM Antikörper

Target: PYGM (Phosphorylase, Glycogen, Muscle (PYGM))

Bindungsspezifität: AA 698-727, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PYGM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This PYGM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 698-727 amino acids from the C-terminal region of human PYGM.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PYGM

Target: PYGM (Phosphorylase, Glycogen, Muscle (PYGM))

Andere Bezeichnung: PYGM (PYGM Produkte)

Synonyme: pygb antikoerper, im:7150327 antikoerper, zgc:110706 antikoerper, AI115133 antikoerper, PG antikoerper, Muscpho antikoerper, zgc:63642 antikoerper, phosphorylase, glycogen, muscle L homeolog antikoerper, glycogen phosphorylase, muscle associated antikoerper, phosphorylase, glycogen, muscle A antikoerper, glycogen phosphorylase, muscle form antikoerper, muscle glycogen phosphorylase antikoerper, phosphorylase, glycogen, muscle b antikoerper, pygm.L antikoerper, PYGM antikoerper, pygma antikoerper, THA_70 antikoerper, Pygm antikoerper, pygmb antikoerper

Hintergrund: PYGM catalyzes and regulates the breakdown of glycogen to glucose-1-phosphate. Defects in PYGM are the cause of glycogen storage disease type 5 (GSD5), also known as McArdle disease. GSD5 is a metabolic disorder resulting in myopathy characterized by exercise intolerance, cramps, muscle weakness and recurrent myoglobinuria.

Molekulargewicht: 97 kDa

Gen-ID: 5837

UniProt: P11217

Pathways: Cellular Glucan Metabolic Process