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SOCS6 Antikörper (N-Term)

SOCS6 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5532198
  • Target Alle SOCS6 Antikörper anzeigen
    SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    AA 40-69, N-Term
    Reaktivität
    • 34
    • 27
    • 15
    • 1
    Human
    Wirt
    • 45
    • 3
    • 1
    Kaninchen
    Klonalität
    • 48
    • 1
    Polyklonal
    Konjugat
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SOCS6 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 22
    • 21
    • 13
    • 13
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SOCS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human SOCS6.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SOCS6 Primärantikörper
  • Applikationshinweise
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))
    Andere Bezeichnung
    SOCS6 (SOCS6 Produkte)
    Synonyme
    CIS-4 antikoerper, CIS4 antikoerper, HSPC060 antikoerper, SOCS-4 antikoerper, SOCS-6 antikoerper, SOCS4 antikoerper, SSI4 antikoerper, STAI4 antikoerper, STATI4 antikoerper, socs6 antikoerper, MGC81477 antikoerper, SOCS6 antikoerper, 1500012M23Rik antikoerper, 5830401B18Rik antikoerper, AI447482 antikoerper, Cis4 antikoerper, Cish4 antikoerper, Socs4 antikoerper, socs6l antikoerper, zgc:64107 antikoerper, wu:fb77f06 antikoerper, suppressor of cytokine signaling 6 antikoerper, suppressor of cytokine signaling 6 L homeolog antikoerper, suppressor of cytokine signaling antikoerper, suppressor of cytokine signaling 6b antikoerper, SOCS6 antikoerper, Socs6 antikoerper, socs6.L antikoerper, socs6 antikoerper, socs6b antikoerper
    Hintergrund
    The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
    Molekulargewicht
    60 kDa
    Gen-ID
    9306
    UniProt
    O14544
    Pathways
    JAK-STAT Signalweg, Carbohydrate Homeostasis
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