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SNCAIP Antikörper (C-Term)

SNCAIP Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5532212
  • Target Alle SNCAIP Antikörper anzeigen
    SNCAIP (Synuclein, alpha Interacting Protein (SNCAIP))
    Bindungsspezifität
    • 15
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 593-622, C-Term
    Reaktivität
    • 25
    • 23
    • 16
    • 1
    Human, Maus
    Wirt
    • 36
    • 2
    • 2
    Kaninchen
    Klonalität
    • 39
    • 1
    Polyklonal
    Konjugat
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SNCAIP Antikörper ist unkonjugiert
    Applikation
    • 28
    • 13
    • 13
    • 13
    • 7
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    Immunogen
    This Synphilin-1 (SNCAIP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 593-622 amino acids from the C-terminal region of human Synphilin-1 (SNCAIP).
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SNCAIP Primärantikörper
  • Applikationshinweise
    For WB starting dilution is: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    2 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    SNCAIP (Synuclein, alpha Interacting Protein (SNCAIP))
    Andere Bezeichnung
    Synphilin-1 (SNCAIP Produkte)
    Synonyme
    sncaip antikoerper, MGC88953 antikoerper, SNCAIP antikoerper, LOC100221074 antikoerper, SYPH1 antikoerper, Sph1 antikoerper, Syph1 antikoerper, 2810407O15Rik antikoerper, 4933427B05Rik antikoerper, BB104594 antikoerper, synuclein alpha interacting protein antikoerper, synuclein, alpha interacting protein antikoerper, synuclein, alpha interacting protein (synphilin) antikoerper, SNCAIP antikoerper, sncaip antikoerper, Sncaip antikoerper
    Hintergrund
    Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. Synuclein alpha interacting protein (Synphilin-1) contains several protein-protein interaction domains and interacts with alpha synuclein in neurons. Mutations of SNCAIP have been linked to Parkinson disease. The amino acid sequence of synphilin-1 shows extensive homology with its human counterpart, especially in regions containing ankyrin-like motifs and the coiled-coil domain. Expression of mouse synphilin-1 in tissues is similar to its human counterpart. Synphilin-1 has an important role in the formation of aggregates and cytotoxicity in Parkinson disease and that Dorfin may be involved in the pathogenic process by ubiquitylation of synphilin-1. Role of synphilin-1 in synaptic function and protein degradation and in the molecular mechanisms leading to neurodegeneration in Parkinson disease
    Molekulargewicht
    100 kDa
    Gen-ID
    9627
    UniProt
    Q9Y6H5
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