Leptin Receptor Antikörper (N-Term)
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- Target Alle Leptin Receptor (LEPR) Antikörper anzeigen
- Leptin Receptor (LEPR)
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Bindungsspezifität
- AA 23-52, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Leptin Receptor Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- Immunogen
- This Leptin Receptor (LEPR) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-52 amino acids from the N-terminal region of human Leptin Receptor (LEPR).
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product LEPR Primärantikörper
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- Applikationshinweise
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For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:50~100 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 2 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- Leptin Receptor (LEPR)
- Andere Bezeichnung
- Leptin Receptor (LEPR Produkte)
- Synonyme
- CD295 antikoerper, LEP-R antikoerper, LEPRD antikoerper, OB-R antikoerper, OBR antikoerper, obr antikoerper, cd295 antikoerper, ob-rb antikoerper, Fa antikoerper, LEPROT antikoerper, Leprb antikoerper, Modb1 antikoerper, OB-RGRP antikoerper, Obr antikoerper, db antikoerper, diabetes antikoerper, obese-like antikoerper, obl antikoerper, ObRb antikoerper, Ob-R antikoerper, Ob-RM antikoerper, lepr antikoerper, leptin receptor antikoerper, leptin receptor S homeolog antikoerper, LEPR antikoerper, lepr antikoerper, Lepr antikoerper, lepr.S antikoerper
- Hintergrund
- Leptin, an adipocyte-specific hormone, regulates adipose-tissue mass through hypothalamic effects on satiety and energy expenditure by acting through the leptin receptor (LEPR). LEPR is a single-transmembrane-domain receptor of the cytokine receptor family that is identical to the mouse diabetes (db) gene product. During weight loss, leptin levels decrease, whereas soluble LEPR levels and the receptor bound fraction of leptin increases. The presence of LEPR in the absorptive cells of the small intestine suggests that leptin may have a physiological role in the regulation of nutrient absorption.
- Molekulargewicht
- 132 kDa
- Gen-ID
- 3953
- UniProt
- P48357
- Pathways
- JAK-STAT Signalweg, AMPK Signaling, Feeding Behaviour
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