EGLN3 Antikörper (C-Term)
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- Target Alle EGLN3 Antikörper anzeigen
- EGLN3 (Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3))
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Bindungsspezifität
- AA 203-231, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EGLN3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This EGLN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-231 amino acids from the C-terminal region of human EGLN3.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product EGLN3 Primärantikörper
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- Applikationshinweise
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For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- EGLN3 (Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3))
- Andere Bezeichnung
- EGLN3 (EGLN3 Produkte)
- Synonyme
- zgc:77019 antikoerper, wu:fj78a08 antikoerper, EGLN3 antikoerper, phd3 antikoerper, PHD-3 antikoerper, PHD3 antikoerper, SM-20 antikoerper, 2610021G09Rik antikoerper, AI505553 antikoerper, AI648162 antikoerper, Hif-p4h-3 antikoerper, Phd3 antikoerper, HIFP4H3 antikoerper, HIFPH3 antikoerper, egl-9 family hypoxia-inducible factor 3 antikoerper, egl-9 family hypoxia inducible factor 3 antikoerper, egl-9 family hypoxia-inducible factor 3 L homeolog antikoerper, egln3 antikoerper, EGLN3 antikoerper, egln3.L antikoerper, Egln3 antikoerper
- Hintergrund
- EGLN3 catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. May play a role in cell growth regulation in muscle cells and in apoptosis in neuronal tissue. Promotes cell death through a caspase-dependent mechanism (By similarity).
- Molekulargewicht
- 27 kDa
- Gen-ID
- 112399
- UniProt
- Q9H6Z9
- Pathways
- Positive Regulation of Endopeptidase Activity
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