Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Immunogen
This FRAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-128 amino acids from the Central region of human FRAT1.
FRAT1
Reaktivität: Human
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 488
Applikationshinweise
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
2 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
FRAT1
(Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1))
FRAT1 antikoerper, frat1 antikoerper, AW060382 antikoerper, gbp antikoerper, FRAT1, WNT signaling pathway regulator antikoerper, GSK-3 binding protein FRAT1 antikoerper, frequently rearranged in advanced T cell lymphomas antikoerper, frequently rearranged in advanced T-cell lymphomas antikoerper, frequently rearranged in advanced T-cell lymphomas 1 S homeolog antikoerper, FRAT1 antikoerper, frat1 antikoerper, Frat1 antikoerper, frat1.S antikoerper
Hintergrund
FRAT1 belongs to the GSK-3-binding protein family. It may function in tumor progression and in lymphomagenesis. It positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. It may play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.