PAK4 Antikörper (AA 187-216)

Produktnummer ABIN5534399

Produktdetails anti-PAK4 Antikörper

Target: PAK4 (P21-Activated Kinase 4 (PAK4))

Bindungsspezifität: AA 187-216

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Pak4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of mouse Pak4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PAK4

Target: PAK4 (P21-Activated Kinase 4 (PAK4))

Andere Bezeichnung: Pak4 (PAK4 Produkte)

Synonyme: 5730488L07Rik antikoerper, AW555722 antikoerper, mKIAA1142 antikoerper, im:5916170 antikoerper, wu:fd12b01 antikoerper, zgc:92014 antikoerper, p21 (RAC1) activated kinase 4 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 4 antikoerper, PAK4 antikoerper, Pak4 antikoerper, pak4 antikoerper

Hintergrund: Pak4 activates the JNK pathway. Plays a role in the reorganization of the actin cytoskeleton and in the formation of filopodia. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin. Decreased cofilin activity may lead to stabilization of actin filaments. Phosphorylates ARHGEF2 (By similarity).

Molekulargewicht: 65 kDa

Gen-ID: 70584

UniProt: Q8BTW9

Pathways: RTK Signalweg