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SIGLEC6 Antikörper (C-Term)

SIGLEC6 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5534686
  • Target Alle SIGLEC6 Antikörper anzeigen
    SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))
    Bindungsspezifität
    • 10
    • 8
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 381-412, C-Term
    Reaktivität
    • 51
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 47
    • 3
    • 1
    Kaninchen
    Klonalität
    • 49
    • 2
    Polyklonal
    Konjugat
    • 26
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SIGLEC6 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 28
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SIGLEC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381-412 amino acids from the C-terminal region of human SIGLEC6.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SIGLEC6 Primärantikörper
  • Applikationshinweise
    For IHC-P starting dilution is: 1:50~100

    For WB starting dilution is: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))
    Andere Bezeichnung
    SIGLEC6 (SIGLEC6 Produkte)
    Synonyme
    SIGLEC6 antikoerper, CD327 antikoerper, CD33L antikoerper, CD33L1 antikoerper, CD33L2 antikoerper, CDW327 antikoerper, OBBP1 antikoerper, sialic acid binding Ig like lectin 6 antikoerper, SIGLEC6 antikoerper
    Hintergrund
    SIGLEC6 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells by binding to alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. SIGLEC6, which interacts with LEP, is expressed at high levels in placenta (cyto-and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine. It contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in downmodulation of cellular responses. The phosphorylated ITIM motif binds to the SH2 domain of PTPN6/SHP-1. The gene for SIGLEC6 belongs to the immunoglobulin superfamily.
    Molekulargewicht
    50 kDa
    Gen-ID
    946
    UniProt
    O43699
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