LGR5 Antikörper (AA 689-719)

Produktnummer ABIN5536141

Produktdetails anti-LGR5 Antikörper

Target: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Bindungsspezifität: AA 689-719

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGR5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LGR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 689-719 amino acids from human LGR5.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: For FACS starting dilution is: 1:25

For IHC-P starting dilution is: 1:25

For WB starting dilution is: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.28 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu LGR5

Target: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Andere Bezeichnung: LGR5 (LGR5 Produkte)

Synonyme: lgr5-a antikoerper, lgr5a antikoerper, FEX antikoerper, Gpr49 antikoerper, GPR49 antikoerper, GPR67 antikoerper, GRP49 antikoerper, HG38 antikoerper, leucine-rich repeat containing G protein-coupled receptor 5 L homeolog antikoerper, leucine rich repeat containing G protein coupled receptor 5 antikoerper, leucine rich repeat containing G protein-coupled receptor 5 antikoerper, lgr5.L antikoerper, Lgr5 antikoerper, LGR5 antikoerper

Hintergrund: LGR5/GPR49 is an orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues. Stem cell marker of the intestinal epithelium and the hair follicle. Target gene of Wnt signaling. Expressed in skeletal muscle, placenta, spinal cord, and various region of brain. Expressed at the base of crypts in colonic and small mucosa stem cells. In premalignant cancer expression is not restricted to the cript base. Overexpressed in cancers of the ovary, colon and liver.

Molekulargewicht: 100 kDa

Gen-ID: 8549

UniProt: O75473

Pathways: WNT Signalweg