PSMD4/ASF Antikörper (C-Term)

Produktnummer ABIN5536405

Produktdetails anti-PSMD4/ASF Antikörper

Target: PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))

Bindungsspezifität: AA 347-377, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMD4/ASF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This PSMD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 347-377 amino acids from the C-terminal region of human PSMD4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For IHC-P starting dilution is: 1:50~100

For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PSMD4/ASF

Target: PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))

Andere Bezeichnung: PSMD4 (Psmd4 Produkte)

Synonyme: af-1 antikoerper, mcb1 antikoerper, pub-r5 antikoerper, rpn10 antikoerper, PSMD4 antikoerper, DDBDRAFT_0202512 antikoerper, DDBDRAFT_0232981 antikoerper, DDB_0202512 antikoerper, DDB_0232981 antikoerper, AF antikoerper, AF-1 antikoerper, ASF antikoerper, MCB1 antikoerper, Rpn10 antikoerper, S5A antikoerper, pUB-R5 antikoerper, xrpn10c antikoerper, Af1 antikoerper, Mcb1 antikoerper, angiocidin antikoerper, im:6912672 antikoerper, psmd4 antikoerper, wu:fc68c04 antikoerper, zgc:110247 antikoerper, proteasome 26S subunit, non-ATPase 4 antikoerper, 26S proteasome non-ATPase regulatory subunit 4 antikoerper, 26s proteasome non-atpase regulatory subunit 4 (26s proteasomeregulatory subunit s5a) antikoerper, proteasome 26S subunit, non-ATPase 4 L homeolog antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 antikoerper, proteasome 26S subunit, non-ATPase 4b antikoerper, psmd4 antikoerper, PSMD4 antikoerper, LOC100194679 antikoerper, psmD4 antikoerper, LOC100283637 antikoerper, Smp_000740.1 antikoerper, psmd4.L antikoerper, Psmd4 antikoerper, psmd4b antikoerper

Hintergrund: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSDM4 one of the non-ATPase subunits of the 19S regulator lid.

Molekulargewicht: 41 kDa

Gen-ID: 5710

UniProt: P55036

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway