GAK Antikörper (C-Term)

Produktnummer ABIN5539342

Produktdetails anti-GAK Antikörper

Target: GAK (Cyclin G Associated Kinase (GAK))

Bindungsspezifität: AA 1140-1170, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GAK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1140-1170 amino acids from the C-terminal region of human GAK.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu GAK

Target: GAK (Cyclin G Associated Kinase (GAK))

Andere Bezeichnung: GAK (GAK Produkte)

Synonyme: GAK antikoerper, DKFZp469F1313 antikoerper, gak antikoerper, MGC172462 antikoerper, si:dkeyp-1e8.1 antikoerper, DNAJ26 antikoerper, DNAJC26 antikoerper, D130045N16Rik antikoerper, cyclin G associated kinase antikoerper, GAK antikoerper, gak antikoerper, Gak antikoerper

Hintergrund: GAK, a member of the Ser/Thr protein kinase family, associates with cyclin G and CDK5. It appears to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. GAK localizes to the perinuclear area and to the trans-Golgi network. It is also observed on the plasma membrane, probably at focals adhesions. Expression is ubiquitous, wiht highest levels in testis. The protein contains 1 J domain and 1 tensin domain.

Molekulargewicht: 143 kDa

Gen-ID: 2580

UniProt: O14976