KCNK2 Antikörper (AA 4-14)

Produktnummer ABIN5540445

Produktdetails anti-KCNK2 Antikörper

Target: KCNK2 (Potassium Channel, Subfamily K, Member 2 (KCNK2))

Bindungsspezifität: AA 4-14

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: SASRERPGYT A

Spezifität: This antibody reacts with the 47 kDa TREK-1 in Jurkat cell extract.

Aufreinigung: Protein G affinity

Immunogen: A synthetic peptide derived from the amino sequence 4-14 of human TREK-1, conjugated with KLH

Anwendungsinformationen

Applikationshinweise: ELISA: The antibody (1:500,000 diluted) can detect the TREK-1 peptide coated on ELISA plate at 100 ng/well. Western blot: Dilute approx. 1:3,000 to detect the 47 kDa TREK-1 in Jurkat cell extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.01M PBS, pH 7.4

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu KCNK2

Target: KCNK2 (Potassium Channel, Subfamily K, Member 2 (KCNK2))

Andere Bezeichnung: kcnk2 (KCNK2 Produkte)

Hintergrund: TWIK-related potassium channel 1(TREK-1), also known as K2P2.1, is a two pore domain gated potassium channel that is involved with pain reception. TREK-1 is highly expressed in small sensory neurons and is extensively colocalized with TRPV1. TREK-1 is sensitive to noxious stimuli including extracellular pH , temperature, mechanical force, osmotic pressure and other stimuli. TREK-1 is one of the targets for pain mediator and anaesthesia drug.