Rituximab Antikörper (HRP)

Produktnummer ABIN5541687

Produktdetails anti-Rituximab Antikörper (HRP)

Target: Rituximab

Reaktivität: Bitte anfragen

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Rituximab Antikörper ist konjugiert mit HRP

Applikation: Enzyme Immunoassay (EIA)

Spezifität: This antibody specifically recognises the idiotypic determinants expressed by the Rituximab humanised monoclonal antibody. This antibody does not recognise other CD20 antibodies. It has been used to detect Rituximab bound to the surface of the Raji B cell line, however detection of Rituximab bound 'in vivo' to B-CLL cells has not been demonstrated. It is possible that complement deposition on Rituximab opsonised cells inhibits binding of the anti-Rituximab antibody to cell bound Rituximab (3). Clone MB2A4 has been used in ELISA assays to monitor the levels of rituximab in patient serum following therapy (4,5).

Aufreinigung: Affinity chromatography on Protein G

Immunogen: F(ab)2 fragment of Rituximab

Klon: MB2 A4

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA: 1/20000-1/20000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Rituximab

Target: Rituximab

Abstract: Rituximab Produkte

Substanzklasse: Antibody

Hintergrund: Rituximab is a therapeutic reagent directed against the human CD20 cell surface antigen.