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POMC Antikörper (AA 1-150)

POMC Reaktivität: Human ELISA Wirt: Maus Monoclonal 5D3A10 unconjugated
Produktnummer ABIN5542292
  • Target Alle POMC Antikörper anzeigen
    POMC (Proopiomelanocortin (POMC))
    Bindungsspezifität
    • 16
    • 9
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-150
    Reaktivität
    • 59
    • 39
    • 37
    • 6
    • 1
    • 1
    Human
    Wirt
    • 53
    • 31
    • 1
    Maus
    Klonalität
    • 53
    • 32
    Monoklonal
    Konjugat
    • 55
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser POMC Antikörper ist unkonjugiert
    Applikation
    • 31
    • 28
    • 27
    • 24
    • 17
    • 13
    • 13
    • 13
    • 9
    • 8
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA
    Verwendungszweck
    POMC Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human POMC (AA: 1-150) expressed in E. Coli.
    Klon
    5D3A10
    Isotyp
    IgG2a
    Top Product
    Discover our top product POMC Primärantikörper
  • Applikationshinweise
    ELISA: 1/10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    POMC (Proopiomelanocortin (POMC))
    Andere Bezeichnung
    POMC (POMC Produkte)
    Synonyme
    MSH antikoerper, ACTH antikoerper, pomc antikoerper, SI:bZ36D5.1 antikoerper, SI:bZ36D5.4 antikoerper, si:bz36d5.2 antikoerper, BE antikoerper, Beta-LPH antikoerper, Clip antikoerper, Gamma-LPH antikoerper, Npp antikoerper, Pomc-1 antikoerper, Pomc1 antikoerper, alpha-MSH antikoerper, alphaMSH antikoerper, beta-MSH antikoerper, gamma-MSH antikoerper, CLIP antikoerper, LPH antikoerper, NPP antikoerper, POC antikoerper, Pomc2 antikoerper, proopiomelanocortin a antikoerper, pro-opiomelanocortin-alpha antikoerper, proopiomelanocortin antikoerper, pomca antikoerper, Pomc antikoerper, POMC antikoerper
    Hintergrund

    Description: This gene encodes a preproprotein that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the preproprotein and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used, adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. The antimicrobial melanotropin alpha peptide exhibits antibacterial and antifungal activity. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.

    Aliases: LPH, MSH, NPP, POC, ACTH, CLIP

    Molekulargewicht
    29.4kDa
    Gen-ID
    5443
    HGNC
    5443
    UniProt
    P01189
    Pathways
    Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour
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