FGFR3 Antikörper (AA 529-694)
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- Target Alle FGFR3 Antikörper anzeigen
- FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
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Bindungsspezifität
- AA 529-694
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser FGFR3 Antikörper ist unkonjugiert
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Applikation
- ELISA
- Verwendungszweck
- FGFR3 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human FGFR3 (AA: 529-694) expressed in E. Coli.
- Klon
- 1E3F9
- Isotyp
- IgG2a
- Top Product
- Discover our top product FGFR3 Primärantikörper
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- Applikationshinweise
- ELISA: 1/10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
- Andere Bezeichnung
- FGFR3 (FGFR3 Produkte)
- Synonyme
- FGFR3 antikoerper, LOC100034114 antikoerper, ACH antikoerper, CD333 antikoerper, CEK2 antikoerper, HSFGFR3EX antikoerper, JTK4 antikoerper, FR3 antikoerper, Fgfr-3 antikoerper, Flg-2 antikoerper, HBGFR antikoerper, Mfr3 antikoerper, sam3 antikoerper, fc27h01 antikoerper, wu:fc27h01 antikoerper, fibroblast growth factor receptor 3 antikoerper, fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog antikoerper, FGFR3 antikoerper, fgfr3.S antikoerper, Fgfr3 antikoerper, fgfr3 antikoerper
- Hintergrund
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Description: This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Aliases: ACH, CEK2, JTK4, CD333, HSFGFR3EX
- Molekulargewicht
- 87.7kDa
- Gen-ID
- 2261
- HGNC
- 2261
- UniProt
- P22607
- Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Growth Factor Binding
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