Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Phospholipase C gamma 2 Antikörper (AA 826-985)

PLCG2 Reaktivität: Human ELISA, FACS, ICC Wirt: Maus Monoclonal 2D9E8 unconjugated
Produktnummer ABIN5542312
  • Target Alle Phospholipase C gamma 2 (PLCG2) Antikörper anzeigen
    Phospholipase C gamma 2 (PLCG2)
    Bindungsspezifität
    • 29
    • 19
    • 16
    • 13
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 826-985
    Reaktivität
    • 118
    • 61
    • 47
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    Human
    Wirt
    • 109
    • 9
    Maus
    Klonalität
    • 110
    • 8
    Monoklonal
    Konjugat
    • 54
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Dieser Phospholipase C gamma 2 Antikörper ist unkonjugiert
    Applikation
    • 91
    • 40
    • 40
    • 32
    • 30
    • 22
    • 18
    • 15
    • 11
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Verwendungszweck
    PLCG2 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human PLCG2 (AA: 826-985) expressed in E. Coli.
    Klon
    2D9E8
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    Phospholipase C gamma 2 (PLCG2)
    Andere Bezeichnung
    PLCG2 (PLCG2 Produkte)
    Hintergrund

    Description: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.

    Aliases: FCAS3, APLAID, PLC-IV, PLC-gamma-2

    Molekulargewicht
    147.9kDa
    Gen-ID
    5336
    HGNC
    5336
    UniProt
    P16885
    Pathways
    RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
Sie sind hier:
Kundenservice