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PKN1 Antikörper (AA 442-620)

PKN1 Reaktivität: Human ELISA, IHC, ICC, FACS Wirt: Maus Monoclonal 4H10B1 unconjugated
Produktnummer ABIN5542353
  • Target Alle PKN1 Antikörper anzeigen
    PKN1 (Protein Kinase N1 (PKN1))
    Bindungsspezifität
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 442-620
    Reaktivität
    • 31
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 20
    • 11
    Maus
    Klonalität
    • 21
    • 10
    Monoklonal
    Konjugat
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PKN1 Antikörper ist unkonjugiert
    Applikation
    • 17
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Verwendungszweck
    PKN1 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human PKN1 (AA: 442-620) expressed in E. Coli.
    Klon
    4H10B1
    Isotyp
    IgG2b
    Top Product
    Discover our top product PKN1 Primärantikörper
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    PKN1 (Protein Kinase N1 (PKN1))
    Andere Bezeichnung
    PKN1 (PKN1 Produkte)
    Hintergrund

    Description: The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

    Aliases: DBK, PKN, PAK1, PRK1, PAK-1, PRKCL1, PKN-ALPHA

    Molekulargewicht
    104kDa
    Gen-ID
    5585
    HGNC
    5585
    UniProt
    Q16512
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