PKN1 Antikörper (AA 442-620)
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- Target Alle PKN1 Antikörper anzeigen
- PKN1 (Protein Kinase N1 (PKN1))
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Bindungsspezifität
- AA 442-620
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PKN1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Verwendungszweck
- PKN1 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human PKN1 (AA: 442-620) expressed in E. Coli.
- Klon
- 4H10B1
- Isotyp
- IgG2b
- Top Product
- Discover our top product PKN1 Primärantikörper
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- PKN1 (Protein Kinase N1 (PKN1))
- Andere Bezeichnung
- PKN1 (PKN1 Produkte)
- Synonyme
- DBK antikoerper, PAK-1 antikoerper, PAK1 antikoerper, PKN antikoerper, PKN-ALPHA antikoerper, PRK1 antikoerper, PRKCL1 antikoerper, F730027O18Rik antikoerper, Pkn antikoerper, Prkcl1 antikoerper, Stk3 antikoerper, PKN1 antikoerper, 3-2 antikoerper, CG2049 antikoerper, CG2055 antikoerper, CT6637 antikoerper, CT6660 antikoerper, DPKN antikoerper, Dmel\\CG2049 antikoerper, Dpkn antikoerper, PRK2 antikoerper, Pk45C antikoerper, Pk?3 antikoerper, dPKN antikoerper, l(2)06736 antikoerper, l(2)45Ca antikoerper, v(2)rG232 antikoerper, protein kinase N1 antikoerper, protein kinase N1b antikoerper, Protein kinase N antikoerper, PKN1 antikoerper, Pkn1 antikoerper, pkn1b antikoerper, pkn1 antikoerper, Pkn antikoerper
- Hintergrund
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Description: The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Aliases: DBK, PKN, PAK1, PRK1, PAK-1, PRKCL1, PKN-ALPHA
- Molekulargewicht
- 104kDa
- Gen-ID
- 5585
- HGNC
- 5585
- UniProt
- Q16512
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