TTR Antikörper (AA 1-147)
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- Target Alle TTR Antikörper anzeigen
- TTR (Transthyretin (TTR))
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Bindungsspezifität
- AA 1-147
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TTR Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Verwendungszweck
- TTR Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human TTR (AA: 1-147) expressed in E. Coli.
- Klon
- 2E10C5
- Isotyp
- IgG1
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- TTR (Transthyretin (TTR))
- Andere Bezeichnung
- TTR (TTR Produkte)
- Hintergrund
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Description: This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq, Jan 2009]
Aliases: CTS, CTS1, PALB, TBPA, HEL111, HsT2651
- Molekulargewicht
- 15.9kDa
- Gen-ID
- 7276
- HGNC
- 7276
- UniProt
- P02766
- Pathways
- Hormone Transport
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