MIB1 Antikörper (AA 6-221)
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- Target Alle MIB1 Antikörper anzeigen
- MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
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Bindungsspezifität
- AA 6-221
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MIB1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Flow Cytometry (FACS)
- Verwendungszweck
- MIB1 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human MIB1 (AA: 6-221) expressed in E. Coli.
- Klon
- 2A7B1
- Isotyp
- IgG1
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
- Andere Bezeichnung
- MIB1 (MIB1 Produkte)
- Hintergrund
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Description: This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).
Aliases: MIB, DIP1, ZZZ6, DIP-1, LVNC7, ZZANK2
- Molekulargewicht
- 110kDa
- Gen-ID
- 57534
- HGNC
- 4741
- UniProt
- Q86YT6
- Pathways
- SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
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