JARID2 Antikörper (AA 1097-1246)

Produktnummer ABIN5542458

Produktdetails anti-JARID2 Antikörper

Target: JARID2 (Jumonji, AT Rich Interactive Domain 2 (JARID2))

Bindungsspezifität: AA 1097-1246

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser JARID2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Verwendungszweck: JARID2 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human JARID2 (AA: 1097-1246) expressed in E. Coli.

Klon: 7H1B3

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu JARID2

Target: JARID2 (Jumonji, AT Rich Interactive Domain 2 (JARID2))

Andere Bezeichnung: JARID2 (JARID2 Produkte)

Hintergrund:

Description: This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies.

Aliases: JMJ

Molekulargewicht: 139kDa

Gen-ID: 3720

HGNC: 3720

UniProt: Q92833

Pathways: Chromatin Binding