TERT Antikörper (AA 1029-1132)

Produktnummer ABIN5542472

Produktdetails anti-TERT Antikörper

Target: TERT (Telomerase Reverse Transcriptase (TERT))

Bindungsspezifität: AA 1029-1132

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TERT Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Verwendungszweck: TERT Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human TERT (AA: 1029-1132) expressed in E. Coli.

Klon: 3H2C12

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu TERT

Target: TERT (Telomerase Reverse Transcriptase (TERT))

Andere Bezeichnung: TERT (TERT Produkte)

Synonyme: CMM9 antikoerper, DKCA2 antikoerper, DKCB4 antikoerper, EST2 antikoerper, PFBMFT1 antikoerper, TCS1 antikoerper, TP2 antikoerper, TRT antikoerper, hEST2 antikoerper, hTRT antikoerper, chTERT antikoerper, Tert antikoerper, ATTERT antikoerper, F5E19.190 antikoerper, F5E19_190 antikoerper, telomerase reverse transcriptase antikoerper, tert antikoerper, TR antikoerper, est2 antikoerper, tcs1 antikoerper, telomerase antikoerper, tert-A antikoerper, tp2 antikoerper, trt antikoerper, xTERT antikoerper, telomerase reverse transcriptase antikoerper, Telomerase Reverse Transcriptase antikoerper, Tertp antikoerper, Telomerase catalytic subunit antikoerper, telomerase reverse transcriptase L homeolog antikoerper, TERT antikoerper, trt-1 antikoerper, Tert antikoerper, tert antikoerper, CMU_003490 antikoerper, VDBG_04487 antikoerper, GL50803_16225 antikoerper, tert.L antikoerper

Hintergrund:

Description: Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified, the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.

Aliases: TP2, TRT, CMM9, EST2, TCS1, hTRT, DKCA2, DKCB4, hEST2, PFBMFT1

Molekulargewicht: 127kDa

Gen-ID: 7015

HGNC: 7015

UniProt: O14746

Pathways: Telomere Maintenance