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TERT Antikörper (AA 1029-1132)

TERT Reaktivität: Human ELISA, IHC, FACS Wirt: Maus Monoclonal 3H2C12 unconjugated
Produktnummer ABIN5542472
  • Target Alle TERT Antikörper anzeigen
    TERT (Telomerase Reverse Transcriptase (TERT))
    Bindungsspezifität
    • 16
    • 16
    • 10
    • 10
    • 7
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1029-1132
    Reaktivität
    • 102
    • 37
    • 20
    • 5
    • 1
    • 1
    Human
    Wirt
    • 106
    • 4
    • 1
    Maus
    Klonalität
    • 98
    • 13
    Monoklonal
    Konjugat
    • 50
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser TERT Antikörper ist unkonjugiert
    Applikation
    • 66
    • 48
    • 37
    • 27
    • 17
    • 14
    • 13
    • 13
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Verwendungszweck
    TERT Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human TERT (AA: 1029-1132) expressed in E. Coli.
    Klon
    3H2C12
    Isotyp
    IgG1
    Top Product
    Discover our top product TERT Primärantikörper
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    TERT (Telomerase Reverse Transcriptase (TERT))
    Andere Bezeichnung
    TERT (TERT Produkte)
    Hintergrund

    Description: Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified, the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.

    Aliases: TP2, TRT, CMM9, EST2, TCS1, hTRT, DKCA2, DKCB4, hEST2, PFBMFT1

    Molekulargewicht
    127kDa
    Gen-ID
    7015
    HGNC
    7015
    UniProt
    O14746
    Pathways
    Telomere Maintenance
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