CBX3 Antikörper (AA 1-183)

Produktnummer ABIN5542474

Produktdetails anti-CBX3 Antikörper

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Bindungsspezifität: AA 1-183

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CBX3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Verwendungszweck: CBX3 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CBX3 (AA: 1-183) expressed in E. Coli.

Klon: 6D1C4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu CBX3

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Andere Bezeichnung: CBX3 (CBX3 Produkte)

Synonyme: HECH antikoerper, HP1-GAMMA antikoerper, HP1Hs-gamma antikoerper, Hp1-gamma antikoerper, HP1g antikoerper, M32 antikoerper, cbx3 antikoerper, cbx3a antikoerper, xhp1g antikoerper, wu:fb61b02 antikoerper, zgc:153397 antikoerper, chromobox 3 antikoerper, chromobox 3 L homeolog antikoerper, chromobox protein homolog 3 pseudogene antikoerper, chromobox homolog 3a (HP1 gamma homolog, Drosophila) antikoerper, CBX3 antikoerper, Cbx3 antikoerper, cbx3.L antikoerper, LOC100355282 antikoerper, cbx3a antikoerper

Hintergrund:

Description: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.

Aliases: HECH, HP1-GAMMA, HP1Hs-gamma

Molekulargewicht: 20.8kDa

Gen-ID: 11335

HGNC: 11335

UniProt: Q13185