CIRBP Antikörper (AA 1-90)

Produktnummer ABIN5542478

Produktdetails anti-CIRBP Antikörper

Target: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Bindungsspezifität: AA 1-90

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CIRBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Verwendungszweck: CIRBP Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CIRBP (AA: 1-90) expressed in E. Coli.

Klon: 6E12B3

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu CIRBP

Target: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Andere Bezeichnung: CIRBP (CIRBP Produkte)

Hintergrund:

Description: Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3-untranslated regions (3-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.

Aliases: CIRP

Molekulargewicht: 18.6kDa

Gen-ID: 1153

HGNC: 4233

UniProt: Q14011

Pathways: Ribonucleoprotein Complex Subunit Organization