LRP1 Antikörper (AA 20-155)
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- Target Alle LRP1 Antikörper anzeigen
- LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))
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Bindungsspezifität
- AA 20-155
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser LRP1 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Verwendungszweck
- LRP1 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human LRP1 (AA: 20-155) expressed in E. Coli.
- Klon
- 3F12E2
- Isotyp
- IgG1
- Top Product
- Discover our top product LRP1 Primärantikörper
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))
- Andere Bezeichnung
- LRP1 (LRP1 Produkte)
- Hintergrund
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Description: The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients.
Aliases: APR, LRP, A2MR, CD91, APOER, LRP1A, TGFBR5, IGFBP3R
- Molekulargewicht
- 50.5kDa
- Gen-ID
- 4035
- HGNC
- 4035
- UniProt
- Q07954
- Pathways
- Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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