DDX3X Antikörper (AA 518-661)

Produktnummer ABIN5542508

Produktdetails anti-DDX3X Antikörper

Target: DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

Bindungsspezifität: AA 518-661

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DDX3X Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Verwendungszweck: DDX3X Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human DDX3X (AA: 518-661) expressed in E. Coli.

Klon: 3B9E3

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu DDX3X

Target: DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

Andere Bezeichnung: DDX3X (DDX3X Produkte)

Synonyme: DBX antikoerper, DDX14 antikoerper, DDX3 antikoerper, HLP2 antikoerper, D1Pas1-rs2 antikoerper, Ddx3 antikoerper, Fin14 antikoerper, An3 antikoerper, pl10 antikoerper, DDX3X antikoerper, DEAD-box helicase 3, X-linked antikoerper, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked antikoerper, DEAD-box helicase 3, X-linked L homeolog antikoerper, DDX3X antikoerper, Ddx3x antikoerper, ddx3x.L antikoerper, ddx3x antikoerper

Hintergrund:

Description: The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants.

Aliases: DBX, DDX3, HLP2, DDX14, CAP-Rf

Molekulargewicht: 73.2kDa

Gen-ID: 1654

HGNC: 1654

UniProt: O00571

Pathways: Ribonucleoprotein Complex Subunit Organization, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Ribosome Assembly