LEF1 Antikörper (AA 33-138)
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- Target Alle LEF1 Antikörper anzeigen
- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
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Bindungsspezifität
- AA 33-138
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser LEF1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Verwendungszweck
- LEF1 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human LEF1 (AA: 33-138) expressed in E. Coli.
- Klon
- 1A4B11
- Isotyp
- IgG1
- Top Product
- Discover our top product LEF1 Primärantikörper
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- Applikationshinweise
- ELISA: 1/10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
- Andere Bezeichnung
- LEF1 (LEF1 Produkte)
- Synonyme
- LEF1 antikoerper, 3000002B05 antikoerper, AI451430 antikoerper, Lef-1 antikoerper, LEF-1 antikoerper, TCF10 antikoerper, TCF1ALPHA antikoerper, TCF7L3 antikoerper, lymphoid enhancer binding factor 1 antikoerper, lymphoid enhancer-binding factor 1 antikoerper, lymphoid enhancer factor XLEF-1B antikoerper, LEF1 antikoerper, lef1 antikoerper, Lef1 antikoerper
- Hintergrund
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Description: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
Aliases: LEF-1, TCF10, TCF7L3, TCF1ALPHA
- Molekulargewicht
- 44.2kDa
- Gen-ID
- 51176
- HGNC
- 51176
- UniProt
- Q9UJU2
- Pathways
- WNT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
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