NOTCH3 Antikörper (AA 47-156)
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- Target Alle NOTCH3 Antikörper anzeigen
- NOTCH3 (Notch 3 (NOTCH3))
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Bindungsspezifität
- AA 47-156
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser NOTCH3 Antikörper ist unkonjugiert
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Applikation
- ELISA
- Verwendungszweck
- Notch3 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human Notch3 (AA: 47-156) expressed in E. Coli.
- Klon
- 3E2D9
- Isotyp
- IgG2a
- Top Product
- Discover our top product NOTCH3 Primärantikörper
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- Applikationshinweise
- ELISA: 1/10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- NOTCH3 (Notch 3 (NOTCH3))
- Andere Bezeichnung
- Notch3 (NOTCH3 Produkte)
- Synonyme
- CADASIL antikoerper, CASIL antikoerper, IMF2 antikoerper, AW229011 antikoerper, N3 antikoerper, hpbk antikoerper, fa14b08 antikoerper, notch5 antikoerper, wu:fa14b08 antikoerper, notch 3 antikoerper, NOTCH3 antikoerper, Notch3 antikoerper, notch3 antikoerper
- Hintergrund
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Description: This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Aliases: IMF2, CASIL, CADASIL
- Molekulargewicht
- 243.6kDa
- Gen-ID
- 4854
- HGNC
- 4854
- UniProt
- Q9UM47
- Pathways
- Notch Signalweg
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