TCL1A Antikörper (AA 10-104)
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- Target Alle TCL1A Antikörper anzeigen
- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
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Bindungsspezifität
- AA 10-104
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TCL1A Antikörper ist unkonjugiert
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Applikation
- ELISA, Flow Cytometry (FACS)
- Verwendungszweck
- TCL1A Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human TCL1A (AA: 10-104) expressed in E. Coli.
- Klon
- 2E3A5
- Isotyp
- IgG1
- Top Product
- Discover our top product TCL1A Primärantikörper
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
- Andere Bezeichnung
- TCL1A (TCL1A Produkte)
- Synonyme
- TCL1A antikoerper, Tcl1a antikoerper, TCL1 antikoerper, Tcl1 antikoerper, T-cell leukemia/lymphoma 1A antikoerper, T cell lymphoma breakpoint 1 antikoerper, TCL1A antikoerper, Tcl1 antikoerper, Tcl1a antikoerper
- Hintergrund
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Description: Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).
Aliases: TCL1
- Molekulargewicht
- 13.5kDa
- Gen-ID
- 8115
- HGNC
- 8115
- UniProt
- P56279
- Pathways
- Stem Cell Maintenance
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