p130 Antikörper (AA 939-1139)
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- Target Alle p130 (RBL2) Antikörper anzeigen
- p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
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Bindungsspezifität
- AA 939-1139
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser p130 Antikörper ist unkonjugiert
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Applikation
- ELISA, Flow Cytometry (FACS)
- Verwendungszweck
- RBL2 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human RBL2 (AA: 939-1139) expressed in E. Coli.
- Klon
- 2C8A8
- Isotyp
- IgG1
- Top Product
- Discover our top product RBL2 Primärantikörper
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anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 165-194), (N-Term) antibody
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anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 Reaktivität: Ratte, Maus IF, IHC Wirt: Kaninchen Polyclonal unconjugated
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anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 878-913) antibodyRBL2 Reaktivität: Human, Ratte WB, IF, IHC, IHC (p), IP Wirt: Maus Monoclonal 130P215 unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 417-616) antibodyRBL2 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 Reaktivität: Human, Ratte, Maus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 Reaktivität: Human, Ratte, Maus ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 416-515) antibodyRBL2 Reaktivität: Human ELISA, WB Wirt: Maus Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 Reaktivität: Human, Schimpanse ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
- Andere Bezeichnung
- RBL2 (RBL2 Produkte)
- Synonyme
- RBL2 antikoerper, RBR2 antikoerper, RRB2a antikoerper, PRB2 antikoerper, RBR-2 antikoerper, Rb2 antikoerper, p130 antikoerper, P130 antikoerper, retinoblastoma-like 2 (p130) antikoerper, RB transcriptional corepressor like 2 antikoerper, related to retinoblastoma 2 antikoerper, RBL2 antikoerper, LOC541652 antikoerper, Rbl2 antikoerper
- Hintergrund
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Description: RBL2 is a Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.
Aliases: Rb2, P130
- Molekulargewicht
- 128.4kDa
- Gen-ID
- 5934
- HGNC
- 5934
- UniProt
- Q08999
- Pathways
- Zellzyklus, Mitotic G1-G1/S Phases
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