beta 2 Adrenergic Receptor Antikörper (AA 302-413)
-
- Target Alle beta 2 Adrenergic Receptor (ADRB2) Antikörper anzeigen
- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
-
Bindungsspezifität
- AA 302-413
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser beta 2 Adrenergic Receptor Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Verwendungszweck
- ADRB2 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human ADRB2 (AA: 302-413) expressed in E. Coli.
- Klon
- 5G3B5
- Isotyp
- IgG1
- Top Product
- Discover our top product ADRB2 Primärantikörper
-
-
- Applikationshinweise
-
ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
- Target
- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
- Andere Bezeichnung
- ADRB2 (ADRB2 Produkte)
- Hintergrund
-
Description: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
Aliases: BAR, B2AR, ADRBR, ADRB2R, BETA2AR
- Molekulargewicht
- 46.5kDa
- Gen-ID
- 154
- HGNC
- 11293627
- UniProt
- P07550
- Pathways
- cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
-