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PYCARD Antikörper (AA 1-120)

PYCARD Reaktivität: Human WB, ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 1C3D3 unconjugated
Produktnummer ABIN5542580
  • Target Alle PYCARD Antikörper anzeigen
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    Bindungsspezifität
    • 10
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-120
    Reaktivität
    • 56
    • 10
    • 9
    • 1
    • 1
    • 1
    Human
    Wirt
    • 48
    • 6
    • 3
    Maus
    Klonalität
    • 47
    • 10
    Monoklonal
    Konjugat
    • 32
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PYCARD Antikörper ist unkonjugiert
    Applikation
    • 39
    • 22
    • 14
    • 13
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human PYCARD (AA: 1-120) expressed in E. coli.
    Klon
    1C3D3
    Isotyp
    IgG1
    Top Product
    Discover our top product PYCARD Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Target
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    Andere Bezeichnung
    PYCARD (PYCARD Produkte)
    Synonyme
    ASC antikoerper, CARD5 antikoerper, TMS antikoerper, TMS-1 antikoerper, TMS1 antikoerper, 9130417A21Rik antikoerper, Asc antikoerper, TNS1 antikoerper, masc antikoerper, asc1 antikoerper, zAsc antikoerper, zgc:109874 antikoerper, PYD and CARD domain containing antikoerper, PYCARD antikoerper, Pycard antikoerper, pycard antikoerper
    Hintergrund

    Description: This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm, however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.,

    Aliases: ASC, TMS, TMS1, CARD5, TMS-1

    Molekulargewicht
    21.6 kDa
    Gen-ID
    29108
    HGNC
    29108
    Pathways
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
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