PMS2 Antikörper (AA 748-851)
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- Target Alle PMS2 Antikörper anzeigen
- PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
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Bindungsspezifität
- AA 748-851
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PMS2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Verwendungszweck
- PMS2 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human PMS2 (AA: 748-851) expressed in E. Coli.
- Klon
- 1E9D11
- Isotyp
- IgG1
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
- Andere Bezeichnung
- PMS2 (PMS2 Produkte)
- Synonyme
- HNPCC4 antikoerper, PMS2CL antikoerper, PMSL2 antikoerper, AW555130 antikoerper, Pmsl2 antikoerper, PMS1 homolog 2, mismatch repair system component antikoerper, PMS1 homolog2, mismatch repair system component antikoerper, mismatch repair endonuclease PMS2 antikoerper, PMS2 antikoerper, Pms2 antikoerper, LOC463257 antikoerper, LOC107984056 antikoerper
- Hintergrund
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Description: This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.
Aliases: PMSL2, HNPCC4, PMS2CL
- Molekulargewicht
- 95.8kDa
- Gen-ID
- 5395
- HGNC
- 5395
- UniProt
- P54278
- Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
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