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PMS2 Antikörper (AA 748-851)

PMS2 Reaktivität: Human ELISA, ICC, FACS Wirt: Maus Monoclonal 1E9D11 unconjugated
Produktnummer ABIN5542596
  • Target Alle PMS2 Antikörper anzeigen
    PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
    Bindungsspezifität
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 748-851
    Reaktivität
    • 58
    • 11
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 45
    • 13
    Maus
    Klonalität
    • 36
    • 22
    Monoklonal
    Konjugat
    • 41
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PMS2 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 25
    • 13
    • 12
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Verwendungszweck
    PMS2 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human PMS2 (AA: 748-851) expressed in E. Coli.
    Klon
    1E9D11
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
    Andere Bezeichnung
    PMS2 (PMS2 Produkte)
    Synonyme
    HNPCC4 antikoerper, PMS2CL antikoerper, PMSL2 antikoerper, AW555130 antikoerper, Pmsl2 antikoerper, PMS1 homolog 2, mismatch repair system component antikoerper, PMS1 homolog2, mismatch repair system component antikoerper, mismatch repair endonuclease PMS2 antikoerper, PMS2 antikoerper, Pms2 antikoerper, LOC463257 antikoerper, LOC107984056 antikoerper
    Hintergrund

    Description: This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.

    Aliases: PMSL2, HNPCC4, PMS2CL

    Molekulargewicht
    95.8kDa
    Gen-ID
    5395
    HGNC
    5395
    UniProt
    P54278
    Pathways
    DNA Reparatur, Production of Molecular Mediator of Immune Response
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