KDM2B Antikörper (AA 457-555)

Produktnummer ABIN5542613

Produktdetails anti-KDM2B Antikörper

Target: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Bindungsspezifität: AA 457-555

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KDM2B Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Verwendungszweck: FBXL10 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human FBXL10 (AA: 457-555) expressed in E. Coli.

Klon: 3B7D11

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu KDM2B

Target: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Andere Bezeichnung: FBXL10 (KDM2B Produkte)

Hintergrund:

Description: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.

Aliases: CXXC2, Fbl10, PCCX2, FBXL10, JHDM1B

Molekulargewicht: 152.6kDa

Gen-ID: 84678

HGNC: 84678

UniProt: Q8NHM5

Pathways: Tube Formation, Warburg Effekt