CFHR5 Antikörper (AA 344-569)

Produktnummer ABIN5542640

Produktdetails anti-CFHR5 Antikörper

Target: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Bindungsspezifität: AA 344-569

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CFHR5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Verwendungszweck: CFHR5 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CFHR5 (AA: 344-569) expressed in E. Coli.

Klon: 3A10A5

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu CFHR5

Target: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Andere Bezeichnung: CFHR5 (CFHR5 Produkte)

Synonyme: CFHL5 antikoerper, CFHR5D antikoerper, FHR-5 antikoerper, FHR5 antikoerper, complement factor H related 5 antikoerper, CFHR5 antikoerper

Hintergrund:

Description: This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS).

Aliases: FHR5, CFHL5, FHR-5, CFHR5D

Molekulargewicht: 64.4kDa

Gen-ID: 81494

HGNC: 81494

UniProt: Q9BXR6