SSH1 Antikörper (AA 1032-1044)

Produktnummer ABIN5542668

Produktdetails anti-SSH1 Antikörper

Target: SSH1 (Slingshot Homolog 1 (SSH1))

Bindungsspezifität: AA 1032-1044

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SSH1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Verwendungszweck: SLINGSHOT-1L Antibody

Aufreinigung: Purified antibody

Immunogen: Synthesized peptide fragment of human SLINGSHOT-1L (AA: 1032-1044 ) expressed in E. Coli.

Klon: 6C11G9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu SSH1

Target: SSH1 (Slingshot Homolog 1 (SSH1))

Andere Bezeichnung: SLINGSHOT-1L (SSH1 Produkte)

Synonyme: AW551225 antikoerper, Gm1394 antikoerper, Gm1395 antikoerper, SSH-1 antikoerper, mSSH-1L antikoerper, SSH1L antikoerper, slingshot homolog 1 (Drosophila) antikoerper, slingshot protein phosphatase 1 antikoerper, Ssh1 antikoerper, SSH1 antikoerper

Hintergrund:

Description: The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Aliases: SSH1,SSH1L

Molekulargewicht: 115.5kDa

Gen-ID: 54434

HGNC: 54434

UniProt: Q8WYL5

Pathways: CXCR4-mediated Signaling Events