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Phospholipase C gamma 1 Antikörper (AA 1192-1291)

PLCG1 Reaktivität: Human, Maus WB, ELISA, IHC, ICC, FACS Wirt: Maus Monoclonal 3H1C10 unconjugated
Produktnummer ABIN5542681
  • Target Alle Phospholipase C gamma 1 (PLCG1) Antikörper anzeigen
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    Bindungsspezifität
    • 36
    • 28
    • 13
    • 9
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1192-1291
    Reaktivität
    • 144
    • 135
    • 126
    • 22
    • 10
    • 8
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 149
    • 27
    Maus
    Klonalität
    • 141
    • 35
    Monoklonal
    Konjugat
    • 79
    • 11
    • 9
    • 9
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Dieser Phospholipase C gamma 1 Antikörper ist unkonjugiert
    Applikation
    • 117
    • 52
    • 38
    • 30
    • 27
    • 21
    • 20
    • 16
    • 11
    • 11
    • 7
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human PLCG1 (AA: 1192-1291) expressed in E. coli.
    Klon
    3H1C10
    Isotyp
    IgG1
    Top Product
    Discover our top product PLCG1 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Target
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    Andere Bezeichnung
    PLCG1 (PLCG1 Produkte)
    Synonyme
    NCKAP3 antikoerper, PLC-II antikoerper, PLC1 antikoerper, PLC148 antikoerper, PLCgamma1 antikoerper, plc1 antikoerper, nckap3 antikoerper, plc-ii antikoerper, plc148 antikoerper, plcgamma1 antikoerper, PPLCA antikoerper, AI894140 antikoerper, Cded antikoerper, Plc-1 antikoerper, Plc-gamma1 antikoerper, Plcg-1 antikoerper, fj46f04 antikoerper, wu:fj46f04 antikoerper, wu:fj57a05 antikoerper, phospholipase C gamma 1 antikoerper, phospholipase C gamma 1 L homeolog antikoerper, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 antikoerper, phospholipase C, gamma 1 antikoerper, PLCG1 antikoerper, plcg1.L antikoerper, LOC100633163 antikoerper, Plcg1 antikoerper, plcg1 antikoerper
    Hintergrund

    Description: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.,

    Aliases: PLC1, NCKAP3, PLC-II, PLC148, PLCgamma1

    Molekulargewicht
    148.5 kDa
    Gen-ID
    5335
    HGNC
    5335
    Pathways
    RTK Signalweg, WNT Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling
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