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Cyclin D3 Antikörper

CCND3 Reaktivität: Human WB, IF (cc) Wirt: Kaninchen Monoclonal 4A8 unconjugated
Produktnummer ABIN5557294
  • Target Alle Cyclin D3 (CCND3) Antikörper anzeigen
    Cyclin D3 (CCND3)
    Reaktivität
    • 106
    • 45
    • 36
    • 16
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 92
    • 16
    Kaninchen
    Klonalität
    • 86
    • 22
    Monoklonal
    Konjugat
    • 48
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser Cyclin D3 Antikörper ist unkonjugiert
    Applikation
    • 78
    • 34
    • 30
    • 26
    • 26
    • 19
    • 15
    • 15
    • 10
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    Recombinant human Cyclin D3 protein, around C-terminal 200aa.
    Klon
    4A8
    Isotyp
    IgG
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  • Applikationshinweise
    WB 1:300-5000
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Cyclin D3 (CCND3)
    Andere Bezeichnung
    Cyclin D3 (CCND3 Produkte)
    Synonyme
    zgc:103502 antikoerper, CCND3 antikoerper, 9230106B05Rik antikoerper, AA682053 antikoerper, AL024085 antikoerper, AW146355 antikoerper, C78795 antikoerper, cyclin D3 antikoerper, ccnd3 antikoerper, CCND3 antikoerper, Ccnd3 antikoerper
    Hintergrund

    Synonyms: G1/S-specific cyclin-D3, CCND3

    Background: Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.

    Gen-ID
    896
    UniProt
    P30281
    Pathways
    Zellzyklus, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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