Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Cyclin E1 Antikörper (pThr77)

CCNE1 Reaktivität: Human WB, IF (cc) Wirt: Kaninchen Monoclonal 4G10 unconjugated
Produktnummer ABIN5557296
  • Target Alle Cyclin E1 (CCNE1) Antikörper anzeigen
    Cyclin E1 (CCNE1)
    Bindungsspezifität
    • 26
    • 16
    • 13
    • 11
    • 9
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr77
    Reaktivität
    • 139
    • 35
    • 32
    • 3
    • 2
    • 2
    • 2
    Human
    Wirt
    • 113
    • 25
    • 1
    Kaninchen
    Klonalität
    • 105
    • 34
    Monoklonal
    Konjugat
    • 79
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser Cyclin E1 Antikörper ist unkonjugiert
    Applikation
    • 91
    • 44
    • 42
    • 40
    • 30
    • 27
    • 19
    • 13
    • 11
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    Synthetic peptide derived from human Cyclin E1(T77), around 50-100aa (phospho T77).
    Klon
    4G10
    Isotyp
    IgG
    Top Product
    Discover our top product CCNE1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Cyclin E1 (CCNE1)
    Andere Bezeichnung
    Cyclin E1 (CCNE1 Produkte)
    Hintergrund

    Synonyms: Cyclin E1 phospho T77, p-Cyclin E1 phospho T77, Cyclin E1 Thr77, CCNE 1, CCNE,CCNE1,Cyclin E1 antibody Cyclin Es,Cyclin Et,CyclinE, G1/S specic cyclin E.

    Background: Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.

    Gen-ID
    898
    UniProt
    P24864
    Pathways
    Zellzyklus, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases
Sie sind hier:
Kundenservice