Histone H3.3 Antikörper

Produktnummer ABIN5557308

Produktdetails anti-Histone H3.3 Antikörper

Target: Histone H3.3

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Histone H3.3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant human Histone H3.3 protein, full length.

Klon: 7B12

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-1000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu Histone H3.3

Target: Histone H3.3

Abstract: Histone H3.3 Produkte

Synonyme: H3.3A antikoerper, H3F3 antikoerper, H3-IX antikoerper, H3-X antikoerper, H3.3B antikoerper, H3F3C antikoerper, H3F3B antikoerper, H3 histone family member 3A antikoerper, H3 histone, family 3A antikoerper, H3 histone, family 3B antikoerper, H3 histone, family 3C L homeolog antikoerper, histone H3.3 antikoerper, Histone H3.3 antikoerper, histone H3.3B-like antikoerper, H3F3A antikoerper, H3F3B antikoerper, H3f3a antikoerper, h3f3c.L antikoerper, LOC5567559 antikoerper, Bm1_29875 antikoerper, Bm1_40030 antikoerper, PTRG_03457 antikoerper, Phum_PHUM492720 antikoerper, UREG_07214 antikoerper, PAAG_07099 antikoerper, PITG_06950 antikoerper, PITG_06953 antikoerper, PITG_06955 antikoerper, LOC100361558 antikoerper, LOC100521680 antikoerper

Hintergrund:

Synonyms: H3F3, H3.3A, Histone H3.3, H3F3A, PP781

Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gen-ID: 3020

UniProt: P84243