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Histone H3.3 Antikörper

Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Monoclonal 7B12 unconjugated
Produktnummer ABIN5557308
  • Target Alle Histone H3.3 Antikörper anzeigen
    Histone H3.3
    Reaktivität
    • 33
    • 12
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 32
    • 2
    Kaninchen
    Klonalität
    • 29
    • 5
    Monoklonal
    Konjugat
    • 21
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Histone H3.3 Antikörper ist unkonjugiert
    Applikation
    • 17
    • 15
    • 12
    • 9
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    Recombinant human Histone H3.3 protein, full length.
    Klon
    7B12
    Isotyp
    IgG
    Top Product
    Discover our top product Histone H3.3 Primärantikörper
  • Applikationshinweise
    WB 1:300-1000
    IHC-P 1:200-400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    Histone H3.3
    Abstract
    Histone H3.3 Produkte
    Hintergrund

    Synonyms: H3F3, H3.3A, Histone H3.3, H3F3A, PP781

    Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    Gen-ID
    3020
    UniProt
    P84243
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