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NRF2 Antikörper (pSer40)

Name: NRF2 Antikörper (pSer40)
SKU: ABIN5557501
Price: 490.77 EUR
Availability: InStock

NFE2L2 Reaktivität: Human, Maus, Ratte WB, IHC (p), FACS, IF (cc) Wirt: Kaninchen Monoclonal 7G4 unconjugated

Lane 1: HepG2, Lane 2: Raji lysates probed with Nrf2(S40) (7G4) Monoclonal Antibody at 1:1000 overnight at 4˚C. (NRF2 Antikörper (pSer40))

HepG2 cells were stained with Nrf2(S40) (7G4) Monoclonal Antibody at [1:200] incubated overnight at 4C, followed by secondary antibody incubation, DAPI staining of the nuclei and detection. (NRF2 Antikörper (pSer40))

IF (cc)

A549 cells were stained with Nrf2(S40) (7G4) Monoclonal Antibody at [1:200] incubated overnight at 4C, followed by secondary antibody incubation, DAPI staining of the nuclei and detection. (NRF2 Antikörper (pSer40))

IF (cc)

Paraformaldehyde-fixed, paraffin embedded human tonsil section, Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal serum) at 37°C for 20min, Antibody incubation with Nrf2(S40) (7G4) Monoclonal Antibody at 1:50 overnight at 4°C, followed by a conjugated secondary and DAB staining. (NRF2 Antikörper (pSer40))

IHC (p)

4 Abbildungen

Produktnummer ABIN5557501

Datenblatt (PDF)

Target Alle NRF2 (NFE2L2) Antikörper anzeigen

NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
Bindungsspezifität
20

15

9

9

8

8

7

4

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer40
Reaktivität
112

54

53

6

5

4

3

3

2

1

1

1

1

1
Human, Maus, Ratte
Wirt
104

10

1
Kaninchen
Passende Sekundärantikörper
Klonalität
97

18
Monoklonal
Konjugat
56

10

6

6

4

3

3

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1
Dieser NRF2 Antikörper ist unkonjugiert
Applikation
87

50

24

21

16

15

14

14

12

9

7

2

2

2

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität

Human, Maus, Ratte

Aufreinigung

Purified by Protein A.

Immunogen

Synthetic peptide derived from human Nrf2(S40), around 1-70aa (phospho S40).

Klon

7G4

Isotyp

IgG

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anti-Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) (AA 430-480) antibody
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anti-Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) (Internal Region) antibody
NFE2L2 Reaktivität: Human, Ratte WB, IF, IP, ICC, IHC (p), ChIP Wirt: Kaninchen Polyclonal unconjugated

anti-Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) (AA 366-605) antibody
NFE2L2 Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) (AA 382-604) antibody
NFE2L2 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) (acLys599) antibody
NFE2L2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) (AA 356-589) antibody
NFE2L2 Reaktivität: Human ELISA, IHC Wirt: Maus Monoclonal 1A6G6 unconjugated

anti-Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) (N-Term) antibody
NFE2L2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) (AA 71-170) antibody
NFE2L2 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 1B8 unconjugated

anti-Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) (AA 71-170) antibody
NFE2L2 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 2G7 unconjugated

Applikationshinweise

WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Target

NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Andere Bezeichnung

Nrf2 (NFE2L2 Produkte)

Synonyme

Nrf2 antikoerper, nfe2l2 antikoerper, wu:fc15g09 antikoerper, wu:fj67e03 antikoerper, NF-E2R2 antikoerper, NRF2 antikoerper, AI194320 antikoerper, nuclear factor, erythroid 2-like 2a antikoerper, nuclear factor, erythroid 2 like 2 S homeolog antikoerper, nuclear factor, erythroid 2 like 2 antikoerper, nuclear factor, erythroid derived 2, like 2 antikoerper, nuclear factor, erythroid 2-like 2 antikoerper, nfe2l2a antikoerper, nfe2l2.S antikoerper, NFE2L2 antikoerper, Nfe2l2 antikoerper

Hintergrund

Synonyms: NRF2, Nuclear factor erythroid 2-related factor 2, NF-E2-related factor 2, NFE2-related factor 2, HEBP1, Nuclear factor, erythroid derived 2, like 2, NFE2L2
Background: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.

Gen-ID

4780

UniProt

Q16236

Pathways

ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling